Azidamfenicol
Azidamfenicol
$210.00 - 1 mg
$735.00 - 5 mg
All prices in Australian dollars
- Code
- BIA-A1485
- Synonyms
- Azidoamphenicol, Leukomycin N
- CAS #
- 13838-08-9
- Molecular Formula
- C11H13N5O5
- Molecular Weight
- 295.3
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
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Application Notes
Azidamfenicol is a semi-synthetic chloramphenicol in which the nitro moiety is replaced with a methylsulphone and the dichloroacetamide is replaced with azidoacetamide, first synthesised at Bayer in 1959. Azidamfenicol is a broad spectrum antibiotic with good activity against Gram negative and anaerobic bacteria. Azidamfenicol acts by binding to the 23S sub-unit of the 50S ribosome, inhibiting protein synthesis. Azidamfenicol has received little research attention with only a few literature citations.
References
- 1-p-Nitrophenyl-2-azidoacetylaminopropane derivatives. Meiser W. & Domagk G. 1959 US Patent 2,882,275.