Avenaciolide

Avenaciolide

$256.00 - 0.50 mg

$896.00 - 2.50 mg

All prices in Australian dollars

Code
BIA-A1409
CAS #
16993-42-3
Molecular Formula
C15H22O4
Molecular Weight
266.3
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
Clear

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Application Notes

Avenaciolide, a bicyclic bis-butyrolactone, was isolated from Aspergillus avenaceus in 1963 as an antifungal agent. Avenaciolide inhibits glutamate transport and is also thought to act as an atypical ionophore.

References

  • Avenaciolide, an antifungal lactone from Aspergillus avenaceus. Brookes D. et al., J. Chem. Soc. 1963, 5385.
  • Avenaciolide: a specific inhibitor of glutamate transport in rat liver mitochondria. McGivan J.D. & Chappell J.B. Biochem. J. 1970, 116, 37P.
  • Ionophoric actions of avenaciolide on mitochondrial cations. Harris E.J. & Wimhurst J.M. Arch. Biochem. Biophys. 1974, 162, 426.

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