$256.00 - 1 mg
$896.00 - 5 mg
All prices in Australian dollars
- CAS #
- Molecular Formula
- Molecular Weight
- >95% by HPLC
- Long Term Storage
- Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
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Aureusimine B (phevalin) is a small molecular weight monoketopiperazine formed non-ribosomally by the fusion of phenylalanine and valine. Aureusimine B was isolated from S. aureus in 2010 as one of a pair of related metabolites, controversially identified as virulence factors in the pathology of Golden Staph. Aureusimine B is also an inhibitor of the protease, calpain.
- Staphylococcus aureus nonribosomal peptide secondary metabolites regulate virulence. Wyatt M.A. et al., Science 2010, 329, 294.
- Aureusimines in Staphylococcus aureus are not involved in virulence. Sun F. et al., PLoS 2010, 5, e15103.
- Phevalin, a new calpain inhibitor, from a Streptomyces sp. Alvarez M.E. et al., J. Antibiot. 1995, 48, 1165.