Aureothin

Aureothin

$343.00 - 0.50 mg

$1,201.00 - 2.50 mg

All prices in Australian dollars

Code
BIA-A1009
Synonyms
Distacin, Mycolutein, 74A'', JA 2814K
CAS #
2825-00-5
Molecular Formula
C22H23NO6
Molecular Weight
397.4
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
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Application Notes

Aureothin, an unusual pyranone metabolite, has broad biological actions including antitumor, antimicrobial and insecticidal activities. Aureothin acts by inhibiting oxidoreductase. More recently, aureothin has been shown to be a potent inhibitor of Helicobacter pylori.

References

  • Gamma-pyrone compounds with selective and potent anti-Helicobacter pylori activity. Taniguchi M. et al., J Antibiot. 2000, 53, 844.
  • Two binding sites of inhibitors in NADH: ubiquinone oxidoreductase (complex I). Relationship of one site with the ubiquinone-binding site of bacterial glucose:ubiquinone oxidoreductase. Friedrich T. et al., Eur J Biochem. 1994, 219, 691.

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