Aureothin
Aureothin
$345.00 - 0.50 mg
$1,210.00 - 2.50 mg
All prices in Australian dollars
- Code
- BIA-A1009
- Synonyms
- Distacin, Mycolutein, 74A'', JA 2814K
- CAS #
- 2825-00-5
- Molecular Formula
- C22H23NO6
- Molecular Weight
- 397.4
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
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Application Notes
Aureothin, an unusual pyranone metabolite, has broad biological actions including antitumor, antimicrobial and insecticidal activities. Aureothin acts by inhibiting oxidoreductase. More recently, aureothin has been shown to be a potent inhibitor of Helicobacter pylori.
References
- Gamma-pyrone compounds with selective and potent anti-Helicobacter pylori activity. Taniguchi M. et al., J Antibiot. 2000, 53, 844.
- Two binding sites of inhibitors in NADH: ubiquinone oxidoreductase (complex I). Relationship of one site with the ubiquinone-binding site of bacterial glucose:ubiquinone oxidoreductase. Friedrich T. et al., Eur J Biochem. 1994, 219, 691.