Asperuloside

Asperuloside

$221.00 - 1 mg

$772.00 - 5 mg

All prices in Australian dollars

Code
BIA-A1774
Synonyms
Rubichloric acid, Asperulin
CAS #
14259-45-1
Molecular Formula
C18H22O11
Molecular Weight
414.36
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO.
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Application Notes

Asperuloside is an iridoid monoterpenoid glycoside derived from the Rubiaceae family of flowering plants first reported in 1893. More recently, asperuloside was reported to have been efficiently isolated from Coprosma quadrifida via rapid pressurised hot water extraction by Smith and collaborators at University of Tasmania, Australia. Asperuloside possesses anti-inflammatory, Antiinsectan and phosphatidylinositol-3-kinase (PI3K) inhibitory properties. Asperuloside has been shown to exert its anti-inflammatory effects via suppression of the NF-κB and MAPK signaling pathways.

References

  • The preparation and properties of aucubin, asperuloside and some related glycosides. Trim A.R. & Hill R., Biochem. J. 1952, 50, 310.
  • Practical isolation of asperuloside from Coprosma quadrifida via rapid pressurised hot water extraction. Deans B.J. et al., Aust. J. Chem. 2016, 69, 1219.
  • Response of generalist and specialist insects to qualitative allelochemical variation. Deane-Bowers M. & Puttick G.M., J. Chem. Ecol. 1988, 14, 319.
  • Asperuloside and asperulosidic acid exert an anti-inflammatory effect via suppression of the NF-κB and MAPK signaling pathways in LPS-Induced RAW 264.7 macrophages. He J. et al., Int. J. Mol. Sci. 2018, 19, 2027.

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