Asperindole A

Asperindole A

Asperindole A

$240.00 - 1 mg

$840.00 - 5 mg

All prices in Australian dollars

Code
BIA-A3078
Synonyms
-
CAS #
2416222-17-6
Molecular Formula
C29H32ClNO6
Molecular Weight
526
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol and DMSO.

Download Data Sheets

Product Data Sheet

Application Notes

Asperindole A is an indole-diterpene alkaloid first isolated from a marine-derived Aspergillus sp. by Ivanets et al., Russian Academy of Sciences, Vladivostok in 2018. Asperindole A is active against hormone therapy-resistant PC-3 and 22Rv1, as well as hormone therapy-sensitive human prostate cancer cells. Asperindole A induces apoptosis at low-micromolar concentrations. Asperindole A was inactive as a modulator of spontaneous Ca2+ oscillations (SCOs) in primary cultured neocortical neurons.

References

  • King D.E. et al. (2006). New classification and update on the quinolone antibiotics. Am. Fam. Physician 61, 3741.
  • Peng G-Y.et al. (2021). Neuronal modulators from the coral-associated fungi Aspergillus candidus. Mar. Drugs, 19, 281.

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