Asperindole A is an indole-diterpene alkaloid first isolated from a marine-derived Aspergillus sp. by Ivanets et al., Russian Academy of Sciences, Vladivostok in 2018. Asperindole A is active against hormone therapy-resistant PC-3 and 22Rv1, as well as hormone therapy-sensitive human prostate cancer cells. Asperindole A induces apoptosis at low-micromolar concentrations. Asperindole A was inactive as a modulator of spontaneous Ca2+ oscillations (SCOs) in primary cultured neocortical neurons.