Aspergillusidone D

Aspergillusidone D

$185.00 - 0.25 mg

$650.00 - 1 mg

All prices in Australian dollars

Code
BIA-A3061
Synonyms
-
CAS #
1454585-77-3
Molecular Formula
C19H16Br2O5
Molecular Weight
484.1
Purity
>95% by HPLC
Long Term Storage
Soluble in methanol and DMSO.

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Application Notes

Aspergillusidone D is a dibrominated depsidone of the nidulin family of fungal metabolites. Aspergillusidone D was first isolated from a marine-derived sponge, Aspergillus unguis, only when cultured on PDB media containing KBr. Aspergillusidone D demonstrates a range of bioactivities, including weak cytotoxicity against several human cell lines, aromatase inhibition and antimicrobial activity against B. subtilis, S. aureus and S. cerevisiae.

References

  • Sureram S. et al. (2013). Directed biosynthesis through biohalogenation of secondary metabolites of the marine-derived fungus Aspergillus unguis. RSC Adv., 3, 1781.
  • Morshed M. et al. (2018). Expanding antibiotic chemical space around the nidulin pharmacophore. Org. Biomol. Chem., 16, 3038.

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