Aspartimide, R-

Aspartimide, R-

$50.00 - 1 mg

$176.00 - 5 mg

All prices in Australian dollars

Code
BIA-A2229
CAS #
404887-22-5
Molecular Formula
C4H6N2O2
Molecular Weight
114.1
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO
Clear

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Application Notes

R-Aspartimide ((R)-3-aminopyrrolidine-2,5-dione) is the cyclic amine formed by the dehydration of the amino acid, D-asparagine. The formation of aspartimides is a common synthetic by-product of peptide chemistry in aspartic acids there is little in the literature describing the occurrence and role of this cyclic metabolite. Despite R-aspartimide’s close relationship to the proteogenic amino acids its biological role is largely unexplored.

References

  • Problem of aspartimide formation in Fmoc-based solid phase peptide synthesis using Dmab group to protect side chain of aspartic acid. Ruczynski J. et al. J Pept Sci. 2008, 14, 335.

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