Ascomycin
Ascomycin
$180.00 - 1 mg
$630.00 - 5 mg
All prices in Australian dollars
- Code
- BIA-A1237
- Synonyms
- L 683590, FR 900520, Immunomycin, FK 520, WS 7238A, NSC 106410
- CAS #
- 104987-12-4
- Molecular Formula
- C43H69NO12
- Molecular Weight
- 792
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
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Application Notes
Ascomycin is a macrocyclic lactone closely related to tacrolimus and rapamycin. Ascomycin is isolated from several species of Streptomyces and was first reported in 1962. Ascomycin exhibits limited, potent antifungal activity but has found considerable utility as an immunosuppressant.
References
- FR-900520 and FR-900523, novel immunosuppressants isolated from a Streptomyces. II. Fermentation, isolation and physico-chemical and biological characteristics. Hatanaka H. et al., J. Antibiot. 1988, 41, 1592.
- Identity of immunospressant FR-900520 with ascomycin. Morisaki M. & Arai T. J. Antibiot. 1992, 45, 126.