Ascomycin

Ascomycin

$165.00 - 1 mg

$578.00 - 5 mg

All prices in Australian dollars

Code
BIA-A1237
Synonyms
L 683590, FR 900520, Immunomycin, FK 520, WS 7238A, NSC 106410
CAS #
104987-12-4
Molecular Formula
C43H69NO12
Molecular Weight
792
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
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Application Notes

Ascomycin is a macrocyclic lactone closely related to tacrolimus and rapamycin. Ascomycin is isolated from several species of Streptomyces and was first reported in 1962. Ascomycin exhibits limited, potent antifungal activity but has found considerable utility as an immunosuppressant.

References

  • FR-900520 and FR-900523, novel immunosuppressants isolated from a Streptomyces. II. Fermentation, isolation and physico-chemical and biological characteristics. Hatanaka H. et al., J. Antibiot. 1988, 41, 1592.
  • Identity of immunospressant FR-900520 with ascomycin. Morisaki M. & Arai T. J. Antibiot. 1992, 45, 126.

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