Aranciamycin A

Aranciamycin A

$232.00 - 0.50 mg

$813.00 - 2.50 mg

All prices in Australian dollars

Code
BIA-A1970
CAS #
960622-70-2
Molecular Formula
C26H28O10
Molecular Weight
500.49
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO
Clear

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Application Notes

Aranciamycin A is an anthracycline bearing a methyl-L-rhamnose sugar in the 2-O position. Aranciamycin A has antitumor and Gram positive antibiotic activity and is a potent inhibitor of Clostridium histolyticum collagenase, with an IC50 = 3.7 x 10-​7M.

References

  • Metabolites of microorganisms. Aranciamycin. Keller-Schierlein W. et al. Helv Chim Acta 1970, 53, 779.
  • The sugar component of aranciamycin: 2-0-methyl-L-rhamnose. Keller-Schierlein W. and Muller A. Experientia 1970, 26, 929.
  • Aranciamycin analogs generated by combinatorial biosynthesis show improved antitumor activity. Luzhetskyy A. et al. Appl Microbiol Biotech 2008, 80, 15.

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