$233.00 - 1 mg
$816.00 - 5 mg
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- Actinophenol, NSC 58413
- CAS #
- Molecular Formula
- Molecular Weight
- >95% by HPLC
- Long Term Storage
- Soluble in methanol or DMSO
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Actiphenol is a glutarimide antibiotic first reported in 1956 with antifungal and antitumor activity. Actiphenol is more active against coxsackievirus B3, influenza virus A, and herpes simplex virus 2 than synthetic glutarimides. The production of actiphenol and cycloheximide in Streptomyces is governed by the one gene cluster, an acyltransferase-less type I polyketide synthase.
- Sttoffwechselprodukte von Actinomyceten, Actiphenol. Highet R.J. and Prelog J. Helv Chim Acta 1956 42: 1523–1526 (1956)
- Synthesis and antiviral activities of synthetic glutarimide derivatives. Ji X. et al. Chem. Pharm. Bull. 2010, 58, 1436.
- Cycloheximide and actiphenol production in Streptomyces sp. YIM56141 governed by single biosynthetic machinery featuring an acyltransferase-less type I polyketide synthase. Yin M. et al. Org. letters 2014, 16, 3072.