Acetylchrysomycin B, 4′-

Acetylchrysomycin B, 4′-

$189.00 - 0.50 mg

$662.00 - 2.50 mg

All prices in Australian dollars

Synonyms
Acetylchrysomycin M
CAS #
NA
Molecular Formula
C30H30O10
Molecular Weight
550.6
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO
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Application Notes

4’-Acetylchrysomycin B and its co-metabolite, 4’-acetylchrysomycin A, were isolated during a screen for antitumor agents. Acetylation of chyrsomycin B increase cytotoxicity. Acetylchyrsomycins are active against Gram-positive bacteria, including MRSA and VRE, with MICs of 0.5-2 μg ml-1 to >64 μg ml-1 for 4'-acetylchrysomycin A and B, respectively.

References

  • Structures and biological activities of novel 4'-acetylated analogs of chrysomycins A and B. Wada S. et al. J. Antibiot. 2017, 70, 1078.

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