Acetylchrysomycin B, 4′-
Acetylchrysomycin B, 4′-
$215.00 - 0.50 mg
$755.00 - 2.50 mg
All prices in Australian dollars
- Code
- BIA-A2349
- Synonyms
- Acetylchrysomycin M
- CAS #
- NA
- Molecular Formula
- C30H30O10
- Molecular Weight
- 550.6
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in methanol or DMSO
Download Data Sheets
Application Notes
4’-Acetylchrysomycin B and its co-metabolite, 4’-acetylchrysomycin A, were isolated during a screen for antitumor agents. Acetylation of chyrsomycin B increase cytotoxicity. Acetylchyrsomycins are active against Gram-positive bacteria, including MRSA and VRE, with MICs of 0.5-2 μg ml-1 to >64 μg ml-1 for 4'-acetylchrysomycin A and B, respectively.
References
- Structures and biological activities of novel 4'-acetylated analogs of chrysomycins A and B. Wada S. et al. J. Antibiot. 2017, 70, 1078.
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