Acetylchloramphenicol, 1-
Acetylchloramphenicol, 1-
$180.00 - 0.25 mg
$630.00 - 1 mg
All prices in Australian dollars
- Code
- BIA-A2357
- Synonyms
- 1-O-Acetylchloramphenicol, Chloramphenicol 1-acetate
- CAS #
- 23214-93-9
- Molecular Formula
- C13H14Cl2N2O6
- Molecular Weight
- 365.17
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in methanol or DMSO
Download Data Sheets
Application Notes
1-Acetylchloramphenicol is an isomer ofchloramphenicol acetate, a naturally-occurring co-metabolite of chloramphenicol in Streptomyces venezuelae albeit with significantly lower potency. Chloramphenicol acetate is the major product of chloramphenicol acetyltransferase, the major resistance mechanism to chloramphenicol.
References
- Isolation of 3′-O-acetylchloramphenicol: A possible intermediate in chloramphenicol biosynthesis. Gross F. et al., Bioorg. Med. Chem. Letters 2002, 12, 283.
- Chloramphenicol acetyltransferase Shaw W.V. & Leslie A.G.W. Ann. Rev. Biophys. Biophys. Chem. 1991, 20, 363.
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