Acetylchloramphenicol, 1-

Acetylchloramphenicol, 1-

$158.00 - 0.25 mg

$553.00 - 1 mg

All prices in Australian dollars

Synonyms
1-O-Acetylchloramphenicol, Chloramphenicol 1-acetate
CAS #
23214-93-9
Molecular Formula
C13H14Cl2N2O6
Molecular Weight
365.17
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO
Clear

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Application Notes

1-Acetylchloramphenicol is an isomer ofchloramphenicol acetate, a naturally-occurring co-metabolite of chloramphenicol in Streptomyces venezuelae with albeit significantly lower potency. Chloramphenicol acetate is the major product of chloramphenicol acetyltransferase, the major resistance mechanism to chloramphenicol.

References

  • Isolation of 3′-O-acetylchloramphenicol: A possible intermediate in chloramphenicol biosynthesis. Gross F. et al., Bioorg. Med. Chem. Letters 2002, 12, 283.
  • Chloramphenicol acetyltransferase Shaw W.V. & Leslie A.G.W. Ann. Rev. Biophys. Biophys. Chem. 1991, 20, 363.

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