Xanthyletin

Xanthyletin

$189.00 - 1 mg

$662.00 - 5 mg

All prices in Australian dollars

Synonyms
2,2-Dimethylchromenocoumarin
CAS #
553-19-5
Molecular Formula
C14H12O3
Molecular Weight
228.25
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO.
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Application Notes

Xanthyletin, a dimethylpyranocoumarin structurally related to psoralen, is the active principal of Luvanga scandens widely used in Hindu medicine. Xanthyletin was isolated from the New Guinea tree, Flindersia pimenteliana, by Taylor and Ritchie, University of Sydney, Australia in 1975. Xanthyletin is an inhibitor of platelet aggregation induced by arachidonic acid and collagen, and is active against L-1210 cell line in vitro.

References

  • The chemical constituents of Australian Flindersia species. XX An examination of F. pimenteliana. Bowden B.F., et al. Aust. J. Chem. 1975, 28, 1393.
  • Structure and biological activity of xanthyletin a new phytoalexin of citrus. Khan A.J. et al., Fruits 1985, 40, 807.
  • Antiplatelet actions of some coumarin compounds isolated from plant sources. Teng C.M. et al., Thromb. Res. 1992, 66, 549.
  • Synthesis and cytotoxic activity of pyranocoumarins of the seselin and xanthyletin series. Magiatis P. et al., J. Nat. Prod. 1998, 61, 982.

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