Unguinol

Unguinol

$199.00 - 1 mg

$697.00 - 5 mg

All prices in Australian dollars

Synonyms
Yasimin; tris-dechloronidulin
CAS #
36587-59-4
Molecular Formula
C19H18O5
Molecular Weight
326.34
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO.
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Application Notes

Unguinol is a depsidone isolated from Aspergillus unguis by researchers at the USDA in 1972. In the same year, Swedish researchers produced unguinol by fermentation of a strain of A. nidulins in chloride-depleted media. Unguinol exhibits weak antibacterial activity but its pharmacology has not been extensively investigated. A discovery screen of fungal extracts identified unguinol as an inhibitor of C4 plant enzyme pyruvate phosphate dikinase (PPDK), a potent herbicide target.

References

  • The chemistry of fungi. Part XXII. Nidulin and nornidulin ("ustin "): chlorine-containing metabolic products of Aspergillus nidulans. Dean F.M. et al., J. Chem. Soc. 1954, 1432.
  • A new depsidone from Aspergillus unguis. Stodola F.H. et al., Phytochem. 1972, 11, 2107.
  • A new depsidone from Aspergillus nidulins. Sierankiewicz J. and Gatenbeck S., Acta Chem. Scand. 1972, 26, 455.

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