Tubermycin B

Tubermycin B

$131.00 - 1 mg

$460.00 - 5 mg

All prices in Australian dollars

Code
BIA-T1524
Synonyms
Phenazine-1-carboxylic acid, X-Pigment, Shenqinmycin
CAS #
2538-68-3
Molecular Formula
C13H8N2O2
Molecular Weight
224.2
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
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Application Notes

Tubermycin B (1-phenazinecarboxylic acid) is a simple phenazine produced by several species of Pseudomonas and Actinomycetes. Tubermycin B is a weakly active antibacterial compound that plays a role in the biocontrol of plant diseases by several Pseudomonas strains. Tubermycin B and related phenazines are important dereplication standards in discovery research to eliminate leads due to high amounts of weakly potent actives.

References

  • Antibiotic substances produced by Pseudomonas aeruginosa. Hays E.E. et al., J. Biol. Chem. 1945, 159, 725.
  • Biosynthesis and regulation of phenazine compounds in Pseudomonas spp. Mavrodi D.V. et al., in Pseudomonas, model organism, pathogen, cell factory. (B.H.A. Verlag GmbH & Co. Germany) 2009, 331.

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