Stachybotrysin B

Stachybotrysin B

$255.00 - 1 mg

$895.00 - 5 mg

All prices in Australian dollars

Code
BIA-S1796
CAS #
2098376-42-0
Molecular Formula
C25H34O6
Molecular Weight
430.53
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO.

Download Data Sheets

Product Data Sheet

Application Notes

Stachybotrysin B is an analogue of a complex of phenylspirodrimanes isolated from the fungus, Stachybotrys chartarum, by collaborating Chinese Key Research Institutes in 2017. Stachybotrysin B is active against HIV but is not cytotoxic. Stachybotrysins have been shown to inhibit osteoclast differentiation in bone marrow macrophage cells via suppression of RANKL-induced activation of p-ERK, p-JNK, p-p38, c-Fos, and NFATc1.

References

  • Stachybotrysins A-G, phenylspirodrimane derivatives from the fungus Stachybotrys chartarum. Zhao J. et al., J. Nat. Prod. 2017, 80, 1819.
  • Stachybotrysin, an osteoclast differentiation inhibitor from the marine-derived fungus Stachybotrys sp. KCB13F013. Kim J.W. et al., J. Nat. Prod. 2016, 79, 2703.

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