Stachybotrysin B
Stachybotrysin B
$255.00 - 1 mg
$895.00 - 5 mg
All prices in Australian dollars
- Code
- BIA-S1796
- CAS #
- 2098376-42-0
- Molecular Formula
- C25H34O6
- Molecular Weight
- 430.53
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in ethanol, methanol, DMF or DMSO.
Download Data Sheets
Application Notes
Stachybotrysin B is an analogue of a complex of phenylspirodrimanes isolated from the fungus, Stachybotrys chartarum, by collaborating Chinese Key Research Institutes in 2017. Stachybotrysin B is active against HIV but is not cytotoxic. Stachybotrysins have been shown to inhibit osteoclast differentiation in bone marrow macrophage cells via suppression of RANKL-induced activation of p-ERK, p-JNK, p-p38, c-Fos, and NFATc1.
References
- Stachybotrysins A-G, phenylspirodrimane derivatives from the fungus Stachybotrys chartarum. Zhao J. et al., J. Nat. Prod. 2017, 80, 1819.
- Stachybotrysin, an osteoclast differentiation inhibitor from the marine-derived fungus Stachybotrys sp. KCB13F013. Kim J.W. et al., J. Nat. Prod. 2016, 79, 2703.
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