Rhizocarpic acid, ent-
Application Notes
ent-Rhizocarpic acid is the D-isomer of the naturally-occurring L-isomer, rhizocarpic acid. ent-Rhizocarpic acid is a member of the pulvinic acid family, with a tetronic acid core bound to the methyl ester of D-phenylalanine. While rhizocarpic acid has moderate but selective activity against the murine myeloma cell line NS-1, ent-rhizocarpic acid is 10-fold less potent in this assay.
References
- King D.E. et al. (2006). New classification and update on the quinolone antibiotics. Am. Fam. Physician 61, 3741.
- James P.J.C. et al. (2023). Synthesis, characterization, and bioactivity of the lichen pigments pulvinamide, rhizocarpic acid, and epanorin and congeners. J. Nat. Prod., 86, 550.



