Resistoflavine

Resistoflavine

$295.00 - 1 mg

$1,035.00 - 5 mg

All prices in Australian dollars

Code
BIA-R1192
Synonyms
A 3733Y, resistoflavin
CAS #
29706-96-5
Molecular Formula
C22H16O7
Molecular Weight
392.4
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in DMF or DMSO. Moderately soluble in methanol or ethanol. Poor water solubility.

Download Data Sheets

Product Data Sheet

Application Notes

Resistoflavine is a rare, boat-shaped, pentacyclic polyketide isolated from several species of Streptomyces, often co-produced with resistomycin. Resistoflavine exhibits weak antibacterial activity against Gram positive and Gram negative bacteria and exhibits potent cytotoxic activity against tumor cell lines in vitro. Resistoflavine inhibits growth, and nucleic acid and protein synthesis in Bacillus subtilis.

References

  • Zur konstitution des antibiotikums resistoflavin. Eckardt K. et al., Tetrahedron 1970, 26, 5875.
  • Effect of the antibiotics resistomycin and resistoflavin on growth, nucleic acid and protein synthesis in Bacillus subtilis. Haupt I. & Eckardt K., Z Allg Mikrobiol. 1972, 12, 575.
  • Resistoflavine, cytotoxic compound from a marine actinomycete, Streptomyces chibaensis AUBN1/7. Gorajana A. et al., Microbiol Res. 2007, 162, 322.

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