Piperafizine A

Piperafizine A

$295.00 - 1 mg

$1,035.00 - 5 mg

All prices in Australian dollars

Code
BIA-P1156
Synonyms
3,6-Dibenzylidene-1-methyl-2,5-dioxopiperazine
CAS #
130603-59-7
Molecular Formula
C19H16N2O2
Molecular Weight
304.3
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.

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Application Notes

Piperafizine A is a methylated diketopiperazine formed by the condensation of phenylalanine, produced by a number of species in the Streptomyces genus. Piperafizine A exhibits little activity in vitro but potentiates vincristine antitumor potency. The mechanism of action has not been characterised.

References

  • Piperafizine A and B, potentiators of cytotoxicity to vincristine. Kamei, H. et al., J. Antibiot., 1990, 43, 1018

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