Piperafizine A
Piperafizine A
$295.00 - 1 mg
$1,035.00 - 5 mg
All prices in Australian dollars
- Code
- BIA-P1156
- Synonyms
- 3,6-Dibenzylidene-1-methyl-2,5-dioxopiperazine
- CAS #
- 130603-59-7
- Molecular Formula
- C19H16N2O2
- Molecular Weight
- 304.3
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
Download Data Sheets
Application Notes
Piperafizine A is a methylated diketopiperazine formed by the condensation of phenylalanine, produced by a number of species in the Streptomyces genus. Piperafizine A exhibits little activity in vitro but potentiates vincristine antitumor potency. The mechanism of action has not been characterised.
References
- Piperafizine A and B, potentiators of cytotoxicity to vincristine. Kamei, H. et al., J. Antibiot., 1990, 43, 1018
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