Pentostatin

Pentostatin

$265.00 - 1 mg

$930.00 - 5 mg

All prices in Australian dollars

Code
BIA-P1273
Synonyms
2'-Deoxycoformycin, Covidaribine, ADAI, CI 825, d-Cof, NSC 218321, PD-ADI, YK 176
CAS #
53910-25-1
Molecular Formula
C11H16N4O4
Molecular Weight
268.3
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Good water solubility.

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Product Data Sheet

Application Notes

Pentostatin is a potent antitumor antibiotic isolated from a Streptomyces species. Pentostatin is a potent inhibitor of adenine deaminase and has been used therapeutically as an antitumor agent.

References

  • A novel adenosine and ara-A deaminase inhibitor, (R)-3-(2-deoxy-b-D-erythro-pentofuranosyl)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol. Woo P. W. K. et al., J. Het. Chem. 1974, 11, 641.
  • Pentostatin: future directions. Klohs W. D. & Kraker A. J. Pharmacol Rev 1992, 44, 459.

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