Palitantin is a polar neutral metabolite isolated from Penicillium palitans by Birkinshaw and Raistrick from the London School of Hygiene and Tropical Medicine in 1936. Palitantin is a cyclitol-like metabolite bearing a heptadiene chain, the conjugated diene giving palitantin its highly characteristic UV spectrum. Palitantin has been found in a number of Penicillium species and is a useful metabolite for chemotaxonomy of the genus. Palitantin is a potent antifungal active with minimal toxicity to mammalian cells.
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