Palitantin

Palitantin

$190.00 - 0.50 mg

$665.00 - 2.50 mg

All prices in Australian dollars

Code
BIA-P1701
CAS #
15265-28-8
Molecular Formula
C14H22O4
Molecular Weight
254.32
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO.

Download Data Sheets

Product Data Sheet

Application Notes

Palitantin is a polar neutral metabolite isolated from Penicillium palitans by Birkinshaw and Raistrick from the London School of Hygiene and Tropical Medicine in 1936. Palitantin is a cyclitol-like metabolite bearing a heptadiene chain, the conjugated diene giving palitantin its highly characteristic UV spectrum. Palitantin has been found in a number of Penicillium species and is a useful metabolite for chemotaxonomy of the genus. Palitantin is a potent antifungal active with minimal toxicity to mammalian cells.

References

  • Studies in the biochemistry of microorganisms. XLIX. Palitantin, C14H22O4 a hitherto undescribed metabolic product of Penicillium palitans Westling. Birkinshaw J.H. and Raistrick H., Biochem. J. 1936, 801.
  • Studies in the biochemistry of micro-organisms. 88. Palitantin. Part 2. Further derivatives and degradation products. Birkinshaw J.H., Biochem. J. 1952, 51, 271.
  • Uber die Isolierung neuer stoffwechselprodukte aus Penicillium brefeldianum Dodge (Isolation of new metabolic products from Penicillium brefeldianum Dodge). Haerri E. et al., Helv. Chim. Acta 1963, 46, 1235.
  • Chemical response of Picea glehnii seed-epiphytic Penicillium species to Pythium vexans under in vitro competitive conditions for mycelial growth. Yamaji K. et al., J. Chem. Ecol. 2005, 31, 805.

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