Ornithine lactam , L-

Ornithine lactam , L-

$65.00 - 1 mg

$230.00 - 5 mg

All prices in Australian dollars

Code
BIA-O2216
Synonyms
(3S)-3-Amino-2-piperidinone
CAS #
34294-79-6
Molecular Formula
C5H10N2O
Molecular Weight
114.15
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO

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Application Notes

L-Ornithine lactam is an endogenous metabolite formed by the dehydration of the non-proteogenic amino acid L-ornithine. Excessive levels of L-ornithine lactam in plasma is diagnostic for a rare autosomal recessive disorder of the urea cycle. Rather whimsically, L-ornithine lactam is used in cosmetics as a skin whitening agent and moisturiser. Ornithine lactam is a biosynthetic precursor of sinefungin. Little is published on the biological activity of ornithine lactam.

References

  • The hyperornithinemia–hyperammonemia-homocitrullinuria syndrome. Martinelli D. et al. J Rare Dis 2015, 10, 29.
  • Cosmetic and topical preparations containing ornithine lactam. Suetsugu M. and Yoshida Y. Jpn. Kokai Tokkyo Koho 2000, JP 2000086481 A 20000328.
  • Identification of ornithine-​lactam converted from arginine in Streptomyces incarnatus NRRL8089. Fukuda K. et al. Okayama Daigaku Nogakubu Gakujutsu Hokoku 2010, 99, 1. 

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