Novobiocic acid is a member of the novobiocin aminocoumarin antibiotic family. Novobiocic acid is a key intermediate in the biosynthesis of novobiocin and an important acid degradation product. While novobiocic acid exhibits little antibacterial activity, it is more potent than novobiocin as a potentiator of etoposide BP-16 activity by inhibiting efflux from tumor cells.
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