Methylviridicatin, O-

Methylviridicatin, O-

$230.00 - 1 mg

$805.00 - 5 mg

All prices in Australian dollars

Code
BIA-M1149
Synonyms
AIDS-089094, 3-Methoxy-4-phenyl-1H-quinolin-2-one
CAS #
6152-57-4
Molecular Formula
C16H13NO2
Molecular Weight
251.3
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.

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Product Data Sheet

Application Notes

3-O-Methylviridicatin is a metabolite produced by several species of Penicillium. Recently, 3-O-methylviridicatin was shown to be a strong inhibitor of TNFα-induced replication of HIV. Lack of availability has hitherto restricted a more intensive investigation of this interesting metabolite.

References

  • Studies in the biochemistry of microorganisms. 93. Cyclopenin, a nitrogen-containing metabolic product of Penicillium cyclopium Westling. Bracken A. et al., Biochem J. 1954, 57, 587.
  • Isolation of viridicatin from Penicillium palitans. J. Arch. Microbiol. 1970, 73, 261.
  • Isolation and characterization of the fungal metabolite 3-O-methylviridicatin as an inhibitor of tumor necrosis factor alpha-induced human immunodeficiency virus replication. Heguy A. et al., Antivir. Chem. Chemother. 1998, 9, 149.

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