Mer-NF5003F

Mer-NF5003F

$255.00 - 1 mg

$895.00 - 5 mg

All prices in Australian dollars

Code
BIA-M1848
Synonyms
F 1839M, NF 5003F, Stachybotrydial, 6'β-Stachybotrydial, ATCC 20928A
CAS #
149598-70-9
Molecular Formula
C23H30O5
Molecular Weight
386.48
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO.

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Application Notes

Mer-NF5003F is a sesquiterpenoid mycotoxin isolated from Stachybotrys strains, first published in 1994 as an avian myeloblastosis virus (AMV) protease inhibitor. Mer-NF5003F is inactive against HIV due to host cell toxicity. An analogue, Mer-NF5003B has been isolated from fungal biomass and dust samples collected in a domestic facility and may be a useful biomarker to assess exposure to potentially harmful S. chartarum contamination.

References

  • Mer-NF5003B, E and F, novel sesquiterpenoids as avian myeloblastosis virus protease inhibitors produced by Stachybotrys sp.. Kaneta R. et al., J. Antibiot. 1994, 47,727.
  • Stachybotrys mycotoxins: from culture extracts to dust samples. Dosen I. et al., Anal. Bioanal. Chem. 2016, 408, 5513.

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