Janthitrem A

Janthitrem A

$215.00 - 0.50 mg

$755.00 - 2.50 mg

All prices in Australian dollars

Code
BIA-J1832
Synonyms
11,12-Epoxyjanthitrem B
CAS #
73561-89-4
Molecular Formula
C37H47NO6
Molecular Weight
601.78
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO.

Download Data Sheets

Product Data Sheet

Application Notes

Janthitrem A is a fluorescent indole-diterpenoid tremorgenic mycotoxin produced by Penicillium janthinellum-infected rye grass discovered by Gallagher and colleagues at CSIR, New Zealand in 1980. Interestingly, the structure of janthitrem A was only published in 2018, some 16 years after janthitrem B and C. Janthitrem A is related to the paspalinines, loitrems, paxillins and terpendoles. Janthitrem A induces tremors in mice and livestock, and reduces feeding in Porina moth (Wiseana cervinata) larvae.

References

  • The janthitrems: fluorescent tremorgenic toxins produced by Penicillium janthinellum isolates from ryegrass pastures. Gallagher R.T. et al., Appl. Env. Microbiol. 1980, 39, 272.
  • High-performance liquid chromatography of the janthitrems: fluorescent tremorgenic mycotoxins produced by Penicillium janthinellum. Lauren D.R., J. Chromatog. A. 1982, 248, 272.
  • Identification and structure elucidation of janthitrems A and D from Penicillium janthinellum and determination of the tremorgenic and anti-insect activity of janthitrems A and B. Babu J.V. et al., J. Agric. Food Chem. 2018, 66, 13116.

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