Fervenulin

Fervenulin

$790.00 - 5 mg

$225.00 - 1 mg

All prices in Australian dollars

Code
BIA-F2448
Synonyms
Fervenuline, NSC 68158, Planomycin, U 7118
CAS #
483-57-8
Molecular Formula
C7H7N5O2
Molecular Weight
193.16
Purity
>95% by HPLC
Long Term Storage
Soluble in methanol or DMSO

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Product Data Sheet

Application Notes

Fervenulin, structurally related to caffeine, was first isolated from Streptomyces fervens in 1959 and reported as a broad spectrum antibiotic, with antineoplastic properties. Fervenulin inhibits egg hatch and increases juvenile mortality of the root-​knot nematode Meloidogyne incognita in vitro, killing up to 100% of second-​stage nematode juveniles when applied at a concentration of 250 µg/mL.

References

  • Fervenulin, a new crystalline antibiotic I. Discovery and biological activities. Deboer C. et al. Antibiot Ann. 1959 – 1960, 7, 227.
  • Free radical mechanisms of action of pyrimidotriazine antibiotics. Orlov V.S. et al. Bioorganicheskaya Khimiya 1983, 9, 556.  
  • Nematicidal activity of fervenulin isolated from a nematicidal actinomycete, Streptomyces sp. CMU-​MH021, on Meloidogyne incognita. Ruanpanun P. et al. World J Microbiol Biotech. 2011, 27, 1373.

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