Dehydrogriseofulvin
Dehydrogriseofulvin
$175.00 - 0.10 mg
$615.00 - 0.50 mg
All prices in Australian dollars
- Code
- BIA-D2553
- Synonyms
- Amudene, Dehydrogriseofulvin
- CAS #
- 3573-90-8
- Molecular Formula
- C17H15ClO6
- Molecular Weight
- 350.75
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in methanol or DMSO
Download Data Sheets
Application Notes
Dehydrogriseofulvin is the biosynthetic precursor of the spirobenzofuran antifungal, griseofulvin, produced by Penicillium sp.. Griseofulvin itself is a potent antifungal that acts by binding to fungal tubulin and inhibiting the mitotic spindle.
References
- Microbial transformation of dehydrogriseofulvin and griseofulvin: Deuterium NMR and mass spectrometric studies of stereochemical courses of microbial hydrogenation and hydroxylation. Sato Y. et al. J Chem Soc Chem Comm. 1977, 12, 415.
- Biosynthesis of griseofulvin. Harris C.M. et al. J Am Chem Soc. 1976, 98, 5380.
- Griseofulvin inhibits fungal mitosis. Gull K. & Trinci A.P.J. Nature 1973, 244, 292.
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