$132.00 - 1 mg
$462.00 - 5 mg
All prices in Australian dollars
- CAS #
- Molecular Formula
- Molecular Weight
- >95% by HPLC
- Long Term Storage
- Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
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Corynecin III (methamphenicol) is a member of a naturally-occurring complex of chloramphenicol-like acyl nitrophenylpropylamines isolated from Corynebacterium hydrocarboclastus in 1972. Corynecin III is active against Gram positive and Gram negative bacteria. Although less potent than chloramphenicol, corynecin III shows a similar species selectivity. Corynecin III was used as a bioisostere of chloroamphenicol to examine the binding relationship of chloramphenicols to DraE virulence factor.
- Production of antibacterial compounds analogues to chloramphenicol by a n-paraffin-grown bacterium. Suzuki T. et al., Agri. Biol. Chem. 1972, 36, 2223.
- The structure of corynecins; chloramphenicol by a n-paraffin-grown bacterium. Shirahata K. et al., Agri. Biol. Chem. 1972, 36, 2229.
- A structural study of the interaction between the Dr haemagglutinin DraE and derivatives of chloramphenicol. Pettigrew D.M. et al., Acta Cryst. Set. D 2009, 65, 513.