Cepharanthine

Cepharanthine

Cepharanthine

$190.00 - 0.5 mg

$665.00 - 2.5 mg

All prices in Australian dollars

Code
BIA-C3175
Synonyms
(+)-Cepharanthine, Cepharanthin, Cepharantin, O-Methylcepharanoline
CAS #
481-49-2
Molecular Formula
C37H38N2O6
Molecular Weight
606.7
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol, DMSO.

Download Data Sheets

Product Data Sheet

Application Notes

Cepharanthine is a bisbenzylisoquinoline alkaloid from tubers of Stephania sp. first reported by Japanese researchers, Kondo and Keimatsu, in 1938. Cepharanthine exhibits a wide range of biological activities, including anti-inflammatory, antitumor, cytoprotective and antibacterial. Cepharanthine inhibits AMP-activated protein kinase (AMPK) and NFκB signaling pathways. Cepharanthine has been used as a therapeutic agent in Japan since the 1950s.

References

  • Über die konstitution des cepharanthins (XLVIII. Mitteil. über sinomenium- und cocculus-alkaloide). Kondon H. & Ichiro K. Berichte der Deutschen Geseslschaft (A & B Series) 1938, 71, 2553.
  • Cepharanthine: An update of its mode of action, pharmacological properties and medical applications. Bally C. Phytomed. 2019, 62, 152956.
  • Cepharanthine, an alkaloid from Stephania cepharantha Hayata, inhibits the inflammatory response in the RAW264.7 cell and mouse models. Huang H. et al. Inflamm. 2014, 37, 235.

Other Products

Related products