Bilaid A

Bilaid A

$263.00 - 1 mg

$921.00 - 5 mg

All prices in Australian dollars

CAS #
2393865-97-7
Molecular Formula
C28H38N4O5
Molecular Weight
510.6
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO
Clear

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Application Notes

Bilaid A (FvVf-OH) is the major analogue of a family of tetrapeptides with an unusual alternating LDLD chirality isolated from an Australian estuarine isolate of Penicillium sp. MST-MF667. Bilaid A is a weak μ-​opioid agonist and the class formed the foundation for the design of more potent analogues, bilorphin and bilactorphin. The role of the bilaids in the fungus’s secondary metabolite cohort is unknown.

References

  • A tetrapeptide class of biased analgesics from an Australian fungus targets the μ-​opioid receptor. Dekan Z. et al. Proc Nat Acad Sci. 2019, 116, 22535.

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