Bafilomycin B1

Bafilomycin B1

$135.00 - 1 mg

$473.00 - 5 mg

All prices in Australian dollars

Code
BIA-B1110
Synonyms
Setamycin
CAS #
88899-56-3
Molecular Formula
C44H65NO13
Molecular Weight
816
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility. NOTE: forms methyl ketal on long term storage in methanol.
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Application Notes

Bafilomycin B1 is a member of a potent family of macrocyclic lactones. Bafilomycin B1 shares the same mode of action and activity as its more accessible A1 analogue. Bafilomycin B1 is broadly active against bacteria, fungi, insects, nematodes and protozoans. Bafilomycin B1 has attracted interest as a potential agent for treating osteoporosis.

References

  • Bafilolides, Potent Inhibitors of the Motility and Development of the Free-Living Stages of Parasitic Nematodes. Lacey E. et al., Int. J. Parasitol. 1995, 25, 349.
  • Structure and function of V-ATPases in osteoclasts: potential therapeutic targets for the treatment of osteolysis. Xu J. et al., Histol. Histopathol. 2007, 22, 443.

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