Aureoquinone
Application Notes
Aureoquinone is a monomeric naphthoquinone originally isolated from the fruiting body of Crepidotus sp. by Berg and colleagues at Hans-Knöll Institute for Natural Products Research, Germany in 2000. Aureoquinone significantly inhibits the adhesion of Candida albicans to both epithelial and endothelial cells in a dose dependent manner and also reduces the release of secreted aspartic proteinase. Aurequinone shares a biosynthetic link with the talcarpones.
References
- Aureoquinone, a new protease inhibitor from Aureobasidium sp. Berg A. et al. J. Antibiot. 2000, 53, 1293.
- Basidiomycete metabolites attenuate virulence properties of Candida albicans in vitro. Falkensammer B. et al. Mycoses 2008, 51, 505.
- Talcarpones A and B: bisnaphthazarin-derived metabolites from the Australian fungus Talaromyces johnpittii sp. nov. MST-FP2594. Lacey A.E. et al. J. Antibiot. 2024, 77, 147.



