Asterric Acid
Asterric Acid
$265.00 - 1 mg
$930.00 - 5 mg
All prices in Australian dollars
- Code
- BIA-A1008
- Synonyms
- Dimethylosoic acid, TAN 1415A, WF 12880A
- CAS #
- 577-64-0
- Molecular Formula
- C17H16O8
- Molecular Weight
- 348.3
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
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Application Notes
Asterric acid is a fungal metabolite with anti-angiogenic properties, isolated from a number of Aspergillus and Penicillium species. It is an inhibitor of vascular endothelial growth factor (VEGF), inhibiting VEGF-induced tube formation of human umbilical vein endothelial cells.
References
- Fungal metabolites, asterric acid derivatives inhibit vascular endothelial growth factor (VEGF)-induced tube formation of HUVECs. Lee H.J. et al., J. Antibiot. 2002, 55, 552.
- Asterric acid, a new endothelin binding inhibitor. Ohashi H. et al., J. Antibiot. 1992, 45, 1684.
- Studies in the biochemistry of micro-organisms. 115. Metabolites of Penicillium frequentans Westling: isolation of sulochrin, asterric acid, (+)-bisdechlorogeodin and two new substituted anthraquinones, questin and questinol. Mahmoodian A. et al., Biochem. J. 1964, 92, 369.
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