Artemisin

Artemisin

$56.00 - 1 mg

$195.00 - 5 mg

All prices in Australian dollars

Code
BIA-A2524
Synonyms
(+)-Arteannuin, (+)-Artemisinin, (+)-Qinghaosu, Arteannuin, Artemef, Artemisine, Artemisinine, HC 101A, Huanghuahaosu, NSC 369397, QHS, Qing Hau Sau, Qing Hau Su, Qinghaosu, Qinghosu
CAS #
63968-64-9
Molecular Formula
C15H22O5
Molecular Weight
282.33
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO
Clear

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Application Notes

Artemisinin is a sesquiterpene lactone isolated from the aerial parts of Artemisia annua L.. Artemisin is best known for its activity against the malaria parasite including resistant strains, but also has antitumor, immunomodulatory and antiviral activity. It has been shown to be effective against schistosomiasis and hepatitis. Artemisin alkylates various proteins in the malaria parasite involved in glycolysis, hemoglobin metabolism, and redox defense.

References

  • Artemisinin: The biosynthetic pathway and its regulation in Artemisia annua, a terpenoid-rich species. Weathers P.J. et al. In Vitro Cellular & Developmental Biology - Plant 2006, 42, 309.
  • Artemisinin activity-based probes identify multiple molecular targets within the asexual stage of the malaria parasites Plasmodium falciparum 3D7. Ismail H.M. Proc Nat Acad Sci 2016, 113, 2080.

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