Aminocephalosporanic acid, 7-

Aminocephalosporanic acid, 7-

$189.00 - 1 mg

$662.00 - 5 mg

All prices in Australian dollars

Code
BIA-A2591
Synonyms
7-ACA, 7-ACS, 7β-Amino-3-acetoxymethylcephemcarboxylic acid, 7β-Aminocephalosporanic acid
CAS #
957-68-6
Molecular Formula
C10H12N2O5S
Molecular Weight
272.28
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO
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Application Notes

7-Aminocephalosporanic acid is derived from cephalosproranic acid, used as a key synthetic intermediate for the production of semi-synthetic cephalosporins. 7-Aminocephalosporanic acid itself is used as the scaffold for design and synthesis on new classes of cephalosporins.

References

  • Construction of a 7-Aminocephalosporanic Acid (7ACA) Biosynthetic Operon and Direct Production of 7ACA in Acremonium Chrysogenum. Isogai T. et al. Biotechnology 1991, 9, 188.
  • Industrial enzymatic production of cephalosporin-based beta-lactams. Barber M.S. et al. Adv. Biochem. Eng. Biotechnol. 2004, 88, 179.
  • Design, synthesis and biological activities of some 7-​aminocephalosporanic acid derivatives. Basoglu S. et al. Eur J Med Chem. 2013, 69, 622.

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