Allantoin

Allantoin

$53.00 - 25 mg

$186.00 - 100 mg

All prices in Australian dollars

Synonyms
(±)-Allantoin, 1-(2,5-Dioxoimidazolidin-4-yl)urea, 5-Ureidohydantoin, Allantion, Allantol, Cordianine, DL-Allantoin, Glyoxyldiureid, Glyoxyldiureide, Glyoxylic diureide, NSC 7606, Psoralon, SD 101, Sebical, Septalan
CAS #
97-59-6
Molecular Formula
C4H6N4O3
Molecular Weight
158.12
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO
Clear

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Application Notes

Allantoin is a metabolic intermediate of purine catabolism in plants widely used in the cosmetic industry as a moisturiser and aid to topical wound healing. Pharmacologically, allantoin has been demonstrated to activate imidazoline-3 (I3) receptors located in pancreatic tissues and ameliorate B-cell damage induced by streptozotocin. In Arabidopsis, allantoin activates abscisic acid (ABA) production, thereby stimulating stress-related gene expression and enhancing seedling tolerance to abiotic stress.

References

  • Antinociception and anti-inflammatory effects of Memora nodosa and allantoin in mice. Florentino I.F. et al. J Ethnopharmacol. 2016, 186, 298.
  • Allantoin ameliorates chemically-induced pancreatic β-cell damage through activation of the imidazoline I3 receptors. Amitani M. et al. Peer J. 2015, e1105/1-e1105/15.
  • Allantoin, a stress-related purine metabolite, can activate jasmonate signaling in a MYC2-regulated and abscisic acid-dependent manner. Hiroshi T. et al. J. Exp. Botany 2016, 67, 2519.

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