$189.00 - 0.10 mg
$662.00 - 0.50 mg
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- 15-Acetylvomitoxin, 15-O-Acetyl-4-deoxynivalenol
- CAS #
- Molecular Formula
- Molecular Weight
- >95% by HPLC
- Long Term Storage
- Soluble in methanol or DMSO
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15-Acetyldeoxynivalenol is a trichothecene mycotoxin produced by Fusarium sp. infecting cereals and grains and posing a health risk to humans and livestock. 15-Acetyldeoxynivalenol has lower acute oral toxicity than deoxynivalenol in mice. In a comparative study of the effects of deoxynivalenol and its 3- and 15-acetyl derivatives on transepithelial transport, gene expression, and cytokine secretion in human intestinal cell Caco-2, all metabolites could induce mRNA expression and production of IL-8, with 15-acetyldeoxynivalenol causing the highest permeability and IL-8 secretion.
- Comparison of acute toxicities of deoxynivalenol (vomitoxin) and 15-acetyldeoxynivalenol in the B6C3F1 mouse. Forsell J.H. et al. Food Chem. Toxicol. 1987, 25, 155.
- Comparative study of deoxynivalenol, 3-acetyldeoxynivalenol, and 15-acetyldeoxynivalenol on intestinal transport and IL-8 secretion in the human cell line Caco-2. Kadota T. et al. Toxicol. In Vitro 2013, 27, 1888.