Acetoxyscirpenol, 15-

Acetoxyscirpenol, 15-

$189.00 - 0.10 mg

$662.00 - 0.50 mg

All prices in Australian dollars

Synonyms
NSC 267030, 4-Deacetylanguidin, Acetoxyscirpenediol, Monoacetoxyscirpenol
CAS #
2623-22-5
Molecular Formula
C17H24O6
Molecular Weight
324.37
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO
Clear

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Application Notes

15-Acetoxyscirpenol is a trichothecene mycotoxin produced by Fusarium sp. infecting cereals and grains and posing a health risk to humans and livestock. 15-Acetoxyscirpenol is also formed by biodegradation of diacetoxyscirpenol. 15-Acetoxyscirpenol induce apoptosis in Jurkat T cells by perturbation of the mitochondrial-membrane potential and PARP cleavage.

References

  • Fusarium toxins of the scirpentriol subgroup: a review. Schollenberger M. et al. Mycpathologia 2007, 164, 101.
  • Biodegradation of mycotoxins: Tales from known and unexplored worlds. Vanhoutte I. et al. Front. Microbiol. 2016; 7: 561.
  • Induction of apoptosis by disturbing mitochondrial-membrane potential and cleaving PARP in Jurkat T cells through treatment with acetoxyscirpenol mycotoxins. Hee Lee D. et al. Biol. Pharm. Bull. 2006, 4, 648.

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