Xanthomegnin

Xanthomegnin

$220.00 - 0.50 mg

$770.00 - 2.50 mg

All prices in Australian dollars

Code
BIA-X3003
Synonyms
NSC-264720
CAS #
1685-91-2
Molecular Formula
C30H22O12
Molecular Weight
574.5
Purity
>95% by HPLC
Long Term Storage
Soluble in methanol and DMSO.

Download Data Sheets

Application Notes

Xanthomegnin is a bis-napthopyrone pigment isolated from several Penicillium and Aspergillus species. Xanthomegnin is a causative agent of death of farm animals fed fungi-infected feed. Xanthomegnin was first reported in 1963 by Day and coworkers from the pathogenic fungi, Trichophyton megnini. Its structure was confirmed 8 years later by X-ray studies by Himes and coworkers. Xanthomegnin is a suspected genotoxic carcinogen. Xanthomegnin is a potent inhibitor of inducible nitric oxide synthase (NOS).

References

  • Day W.C. et al. (1963). Metabolites of pathogenic fungi. II: The isolation of xanthomegnin from Trichophyton Megnini Blanchard 1896. J. Invest. Dermatol., 40, 133.
  • Himes V.L. et al. (1981). Structure of xanthomegnin. Acta Crystallogr., B37, 1932.
  • Alvi K.A. et al. (2000). Identification of inhibitors of inducible nitric oxide synthase from microbial extracts. J Antibiot., 53, 496.

Other Products