X 14885A

X 14885A

X 14885A

$315.00 - 1 mg

$1,105.00 - 5 mg

All prices in Australian dollars

Code
BIA-X3183
Synonyms
Antibiotic X 14885A
CAS #
83917-57-1
Molecular Formula
C27H32N2O7
Molecular Weight
496.6
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol, DMSO.

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Product Data Sheet

Application Notes

X 14885A is a novel divalent cation ionophore closely related to the polyether antibiotic, calcimycin. X 14885A was first isolated from a soil sample collected in Wyoming by Westley and co-workers, Hoffman la-Roche in 1982. X 14885A possesses potent antibacterial activity. The cation affinity of X 14885A is: Mg >Ca, Sr=Ba >>Li, Na, Rb, K, Cs.

References

  • Isolation and characterization of a novel polyether antibiotic of the pyrrolether class, antibiotic X-14885A. Westley J.W. et al. J. Antibiot. 1983, 36, 127.
  • X-14885A, a novel divalent cation ionophore produced by a Streptomyces culture: discovery, fermentation, biological as well as ionophore properties and taxonomy of the producing culture. Liu C.M. J. Antibiot. 1983, 36, 1118.
  • X-14885A: An ionophore closely related to calcimycin (A-23187). NMR, thermodynamic, and kinetic studies of cation selectivity. Albrecht-Gary M.A. et al. J. Am. Chem. Soc. 1989, 111, 8598.

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