spinosyn L, 3′-Ethoxy-
Application Notes
3'-Ethoxyspinosyn L is the minor component in the second generation spinosyn family of bio-insecticides marketed as Spinetoram. 3'-Ethoxyspinosyn L is a semi-synthetic compound prepared by selective ethylation and hydrogenation of Spinosyn L, itself a fermentation product from a biosynthetically blocked mutant of Saccharopolyspora spinosa. As an insecticide, 3'-ethoxyspinosyn L is considered more potent and to have earlier onset and longer duration of action than combinations of spinosyn A and D.
References
- The spinosyn family of insecticides: realizing the potential of natural products research. Kirst H.A. J. Antibiot. 2010, 63, 101.
- Neural network-based QSAR and insecticide discovery: spinetoram. Sparks T.C. et al., J. Comput. Aided Mol. Des. 2008, 22, 393.
- DE-175 (spinetoram), a new semi-synthetic spinosyn in development. Crouse G.D. et al., in Modern Crop Protection Compounds Vol. 3 (eds Kramer W. & Schirmer U.) 2007, 1013.