Spinosyn A
Spinosyn A
$270.00 - 1 mg
$945.00 - 5 mg
All prices in Australian dollars
- Code
- BIA-S1337
- Synonyms
- Lepicidin A, A 83543A, LY 232105
- CAS #
- 131929-60-7
- Molecular Formula
- C41H65NO10
- Molecular Weight
- 732
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
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Application Notes
Spinosyn A is the major component of a complex of unusual, hydrophobic macrocyclic lactones isolated from Saccharopolyspora spinosa in 1991. The 12-membered macrocyclic lactone is fused to form a rare 12-5-6-5 tetracyclic ring system, with the macrocycle and the terminal cyclopentane bearing glycosides. Spinosyn A is a potent insecticide for crop pathogens and ectoparasite control on animals. The spinosyns have a unique mechanism of action involving disruption of nicotinic acetylcholine receptors.
References
- A 83543A-D, unique fermentation-derived tetracyclic macrolides. Kirst H.A. et al., Tetrahedron Lett. 1991, 32, 4839.
- The spinosyn family of insecticides: realizing the potential of natural products research. Kirst H.A. J. Antibiot. 2010, 63, 101.