Spinosyn A

Spinosyn A

$268.00 - 1 mg

$938.00 - 5 mg

All prices in Australian dollars

Code
BIA-S1337
Synonyms
Lepicidin A, A 83543A, LY 232105
CAS #
131929-60-7
Molecular Formula
C41H65NO10
Molecular Weight
732
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
Clear

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Application Notes

Spinosyn A is the major component of a complex of unusual, hydrophobic macrocyclic lactones isolated from Saccharopolyspora spinosa in 1991. The 12-membered macrocyclic lactone is fused to form a rare 12-5-6-5 tetracyclic ring system, with the macrocycle and the terminal cyclopentane bearing glycosides. Spinosyn A is a potent insecticide for crop pathogens and ectoparasite control on animals. The spinosyns have a unique mechanism of action involving disruption of nicotinic acetylcholine receptors.

References

  • A 83543A-D, unique fermentation-derived tetracyclic macrolides. Kirst H.A. et al., Tetrahedron Lett. 1991, 32, 4839.
  • The spinosyn family of insecticides: realizing the potential of natural products research. Kirst H.A. J. Antibiot. 2010, 63, 101.

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