$199.00 - 0.25 mg
$697.00 - 1 mg
All prices in Australian dollars
- CAS #
- Molecular Formula
- Molecular Weight
- >95% by HPLC
- Long Term Storage
- Soluble in ethanol, methanol, DMF or DMSO.
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(+)-Oxanthromicin is an unusual dimeric anthrone co-produced with staurosporine by Streptomyces sp. MST-134270, reported by Capon and co-workers in 2014 as an inducer of the mislocalisation K-Ras on the cell membrane. (+)-Oxanthromicin was also found to act synergistically with staurosporine, a more potent active in this assay. (+)-Oxanthromicin is an enantiomer of (-)-oxanthromicin isolated from an Actinomadura sp. SCC 1646 by researchers at Schering as an antifungal and antibacterial in 1984.
- Oxanthromicin, a novel antibiotic from Actinomadura. Patel M. et al., J. Antibiot. 1984, 37, 413.
- Structure of oxanthromicin (antibiotic 16–550), a novel dimeric anthrone peroxide. Wright J.J.K. et al., J. Chem. Soc. Chem. Commun. 1984, 473.
- Rare Streptomyces sp. polyketides as modulators of K-Ras localisation. Salim A.A. et al., Org. Biomol. Chem. 2014, 12, 4872.