Ivermectin B1a monosaccharide

Ivermectin B1a monosaccharide

$280.00 - 1 mg

$980.00 - 5 mg

All prices in Australian dollars

Code
BIA-I1150
Synonyms
Dihydroavermectin B1 monosaccharide, Ivermectin B1 monosaccharide
CAS #
71837-27-9
Molecular Formula
C41H62O11
Molecular Weight
730.9
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.

Download Data Sheets

Product Data Sheet

Application Notes

Ivermectin monosaccharide is a semi-synthetic produced by selective hydrolysis of the terminal saccharide unit of ivermectin. Ivermectin monosaccharide is a potent inhibitor of nematode larval development, but is devoid of paralytic activity. The monosaccharide is used as a sensitive probe for the detection of some types of ivermectin resistance.

References

  • Ivermectin, a new broad-spectrum antiparasitic agent. Chabala J.C. et al., J. Med. Chem. 1980, 23, 1134.
  • Detection of resistance to ivermectin in Haemonchus contortus. Gill J.G. et al., Int. J. Parasit. 1991, 21, 771.

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