Hesperidin

Hesperidin

$65.00 - 1 mg

$230.00 - 5 mg

All prices in Australian dollars

Code
BIA-H1766
Synonyms
(2S)-Hesperidin, Atripliside B, Cirantin, Hesperetin 7-O-rutinoside, Hesperetin 7-rhamnoglucoside, Hesperetin 7-rutinoside, Hesperidoside, Hesperitin 7-O-rutinoside, NSC 44184
CAS #
520-26-3
Molecular Formula
C28H34O15
Molecular Weight
610.57
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO.

Download Data Sheets

Product Data Sheet

Application Notes

Hesperidin is a flavonoid produced by citrus species, first published in 1943. Hesperidin has a broad pharmacological profile, including Hyperlipidemic, cardioprotective, Hypertensive and antidiabetic activities, mainly attributed to antioxidant activity and suppression of pro-inflammatory cytokine production. Hesperidin causes strongly dose-dependent G2/M phase cell cycle arrest. Hesperidin is also neuroprotective.

References

  • The influence of methyl chalcone of hesperidin on the toxicity of mapharsen in rabbits. Goldstein D.H. et al., Science 1943, 98, 245.
  • Effects of dietary polyphenols on metabolic syndrome features in humans: a systematic review. Amiot M.J. et al., Obes. Rev. 2016, 17, 573.
  • Hesperidin exhibits in vitro and in vivo antitumor effects in human osteosarcoma MG-63 cells and xenograft mice models via inhibition of cell migration and invasion, cell cycle arrest and induction of mitochondrial-mediated apoptosis. Du G.Y. et al., Oncol. Lett. 2018, 6299.

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