Carboline 1-carboxylic acid, β-

Carboline 1-carboxylic acid, β-

$255.00 - 1 mg

$895.00 - 5 mg

All prices in Australian dollars

Code
BIA-C1943
CAS #
26052-96-0
Molecular Formula
C12H8N2O2
Molecular Weight
212.2
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO

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Product Data Sheet

Application Notes

β-Carboline 1-carboxylic acid, isolated from Quassia amara, displays antineuroinflammatory activity in lipopolysaccharide-​induced BV2 microglial cells, inhibiting the production of nitric oxide and prostaglandin E2. Derivatives of β-carboline 1-carboxylic acid inhibit mitogen-activated protein kinase 2. β-Carboline 1-carboxylic acid is also formed endogenously from tryptophan.

References

  • Anti-​neuroinflammatory activities of indole alkaloids from kanjang (Korean fermented soy source) in lipopolysaccharide-​induced BV2 microglial cells. Kim D-C. et al. Food Chem. 2016, 213, 69.
  • Novel tetrahydro-​beta-​carboline-​1-​carboxylic acids as inhibitors of mitogen activated protein kinase-​activated protein kinase 2 (MK-​2). Trujillo J.I. et al. Bioorg Med Chem Lett. 2007, 17, 4657.
  • Tetrahydro-beta-carboline-3-carboxylic acids and contaminants of L-tryptophan. Adachi A. et al. J Chromatogr A. 2000, 881, 501.

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