Carbazomycin A
Application Notes
Carbazomycin A is a minor metabolite of a family of rare carbazoles initially isolated from an unidentified Streptomyces sp. (subsequently identified as Streptomyces ehimense) by researchers at Hiroshima University in 1980. Carbazomycin A is active against Staphylococcus aureus but possesses only weakly active against fungi and yeast. Like all carbazomycins, carbazomycin A possesses a highly distinct UV spectrum and can be readily identifed and de-replicated by HPLC DAD. The mode of action of carbazomycins has received little attention.
References
- New antibiotics, carbazomycins A and B. I. Fermentation, extraction, purification and physico-chemical and biological properties. Sakano K. et al. J Antibiot. 1980, 33, 683.