Benzoxazolinone, 2-

Benzoxazolinone, 2-

$56.00 - 25 mg

$196.00 - 100 mg

All prices in Australian dollars

Code
BIA-B2418
Synonyms
2(3H)-Benzoxazolinone, 2,3-Dihydro-1,3-benzoxazol-2-one, 2-Benzoxazolol, 2-Hydroxybenzoxazole, 2-Oxo-2,3-dihydrobenzoxazole, Benzo[d]oxazol-2(3H)-one, Carbamic acid, (2-hydroxyphenyl)-, γ-lactone, NSC 3812
CAS #
59-49-4
Molecular Formula
C7H5NO2
Molecular Weight
135.12
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO
Clear

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Application Notes

2-Benzoxazolinone is a metabolite produced by rye (Secale cereale) that inhibits germination and growth and causing oxidative damage in target species acting selectively at the G2/M checkpoint of the cell cycle. 2-Benzoxazolinone has diverse pharmacological activities including Antinociception, Anti-inflammatory, antileishmanial, antioxidant, anti-HIV, anticancer, antidepressant, and neuroprotective effects. 2-Benzoxazolinone is a privileged structure for the design of bioactive molecules.

References

  • 2-Benzoxazolinone is a metabolite produced by rye (Secale cereale) that inhibits germination and growth and causing oxidative damage in target species acting selectively at the G2/M checkpoint of the cell cycle. 2-Benzoxazolinone has diverse pharmacological activities including Antinociception, Anti-inflammatory, antileishmanial, antioxidant, anti-HIV, anticancer, antidepressant, and neuroprotective effects. 2-Benzoxazolinone is a privileged structure for the design of bioactive molecules.
  • The natural compound benzoxazolin-2(3H)-one selectively retards cell cycle in lettuce root meristems. Sánchez-Moreiras A-M. et al. Phytochem 2008, 69 2132.
  • Early senescence induced by 2-3H-benzoxazolinone (BOA) in Arabidopsis thaliana. Sánchez-Moreiras A-M. et al. J Plant Physiol 2011, 168, 863.

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